Published by on February 9, 2020
Categories: Literature

The present study was undertaken to test the chemopreventive effects of one herbal medicinal plant, Indigofera aspalathoides, on chemically. The treatment by I. aspalathoides on fibrosarcoma bearing rats has improved the levels Indigofera aspalathoides (I. aspalathoides) treatment for rat arthritis is. Abstract: Civarvembu/ Sivanimba is botanically equated to Indigofera aspalathoides Vahl ex. DC. (Leguminosae). The plant is prescribed for eczema, psoriasis.

Author: Kazizragore Daikora
Country: United Arab Emirates
Language: English (Spanish)
Genre: Technology
Published (Last): 10 May 2013
Pages: 384
PDF File Size: 9.53 Mb
ePub File Size: 5.63 Mb
ISBN: 668-5-57245-962-5
Downloads: 83101
Price: Free* [*Free Regsitration Required]
Uploader: Yozshutilar

Support Center Support Center. Based on the therapeutic applications it was aimed to find out the secondary metabolites present in the whole plant. After cooling, the solution was made up to 5 mL with distilled water.

Remember me Forgot password?

The dried extract and standards were made up to 3 mL with ferric chloride-uranyl acetate reagent. The filtrate was again concentrated in a China dish and dried in vacuum. The Journal of Biological Chemistry. The present study is to further know this plant’s chemopreventive role on some more parameters like total DNA and RNA content and on parameters like hexose, hexosamine, and sialic acid.

Research Journal of Medicinal Plant. Plants have been used to maintain aspalathoidds and vitality, apart from being sources of medicines. The present study was undertaken to indigoferz the chemopreventive effects of one herbal medicinal plant, Indigofera aspalathoideson chemically induced carcinogenesis in rats. Therefore the latest trend is to have a holistic approach of medication in the form of crude extract treatment rather than using the active principles.

Indian J Exp Biol. These findings suggest that the plant extract does not have any toxic side effects.

Fearon ER, Vogelstein B. The distribution of the canals is also variable.

File:Indigofera – Wikimedia Commons

Histopathological Analysis The liver and kidney of control and experimental animals were used for histopathological analysis. Figure 1 represents the body weight changes in both control and experimental animals. Visible observations itself indicated the tumor regression during treatment with indigoferz extract.


The spongy parenchyma cells are three layered; they are lobed and loosely arranged. Enumerates geographic entities where the taxon lives. It aspalatthoides also cover phenomena such as “plant flowering” or “chewing rates”. The method of Warren, [ 24 ], was used to estimate sialic acid. The plant Indigofera aspalathoides belongs to the family Fabaceae Papilonaceae which is popularly known as Sivanar vembu or sivan vembu aspa,athoides Tamil, is a low under shrub with copiously terete spreading branches.

The indigo- carpen and mucronulatol were evaluated for cyclooxygenase-1 COX-1 and cyclooxygenase-2 COX-2 inhibitory activities and antioxidant properties. A textual diagnostic description of the species that is not necessarily structured. Tumors which appeared in about 4 weeks after implantation were highly localized and were maintained by serial transplantation.

The tumor is a large, firm, and pale mass without any capsule and infiltrates into the surrounding tissues. Group I served as normal control, Group II served as fibrosarcoma-induced animals, Group III were fibrosarcoma-bearing animals treated with sapalathoides extracts of Indigofera aspalathoidesand Group IV animals, which were normal healthy animals treated with Indigofera aspalathoides aqueous extract, served as drug control set.

Tubulin-interactive natural products as anticancer agents. It was sighted that the elevated cholesterol level preceedes the observed changes in DNA protein contents suggesting a link between cholesterol and DNA synthetic pathway [36][37].

Herbal Pharmacotherapy ; 6 1: The method aspalatuoides Burton [ 19 ] was followed for DNA estimation. A study on non enzymatic antioxidants such as reduced glutathione, Vitamin C, Vitamin E and total thiols by us also indicated that after the treatment with the aqueous extract of I.

Chemical Constituents of Indigofera Aspalathoides Vahl. Ex. DC.

Therefore, we have used the crude extract of the plant I. Fibrosarcoma is a tumor composed of collagen fibers forming mesenchymal cells of fibroblast and they arise from subcutaneous fibrous tissue [4]. Some studies have indicated that genetic alterations could be involved. Figure 5 depicts the levels of blood glucose in control and experimental animals.


Most of the studies on chemoprevention are based on individual chemicals with well-defined mechanisms. Among them Dodecanoicacid acid, tetradecanoic acid and n-Hexadecanoic acid have the property of anti-oxidant and antimicrobial activities 8. Oral administration of the methanol extract of Indigofera aspalathoides MEIA and Wedelia calendulaceae MEWC at the dose of and mgkg body weight increased the life span and non-viable cell count, decreased tumor volume and viable cell count of the tumor bearing mice, when compared to that of EAC control mice.

Asian Pac J Cancer Prev. Histopathological analysis The liver and kidney of control and experimental animals were used for histopathological analysis.

Article Information

This occurs through a number of mechanisms including a direct damage to Aspaalthoides leading to abnormal transcription of genome. There was also decreased level of neutrophils Indigofra aspalathoides protectionagainst 20 MCA induced experimental fibrosarcoma growth after tansplantation in rats: Early development of protein metabolic perturbation in the liver and skeletal muscle of tumor bearing rats.

Describes biorhythms – those states or conditions characterised by regular repetition in time, whether on the scale of seconds, hours, days, indigoffera seasons. The levels of hexose, hexosamine, and sialic acid in liver and kidney of control and experimental animals.

In the stem and root, the crystals also occur in the ray parenchyma cells. A reagent blank and standards were also carried out.