Published by on January 7, 2020
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Request PDF on ResearchGate | Intérêt des acides biliaires dans la cholestase gravidique | Intrahepatic cholestasis during pregnancy is a risk factor for. La cholestase gravidique a été reliée à des critères de jugement maternels et fœtaux/néonatals indésirables. Du fait que la physiopathologie est mal comprise, . Interventions pour le traitement de la cholestase gravidique. This is not the most recent version of this Review. view the current version 24 June

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La cholestase gravidique Intrahepatic cholestasis of pregnancy. Gravity of the disease comes from the occurrence of fetal complications, in particular prematurity often induced by obstetrical teams and its pulmonary complications, and sudden intra-uterine fetal death.

Besides disturbing pruritus, maternal prognosis is good.

The susceptibility is explained by polymorphisms of genes encoding hepatocytic transport proteins that are important for bile secretion. If you want to subscribe to this journal, see our rates You can purchase this item gravidiqke Pay Per View: You can move this window by clicking on the headline.


Top of the page – Article Outline. Grwvidique signs and biochemical abnormalities normalize rapidly after delivery, at most after 3 to 4 weeks. Personal information regarding our website’s visitors, including their identity, is confidential. Its prevalence in France is of the order of 1 per pregnancies.

Hépato-Gastro & Oncologie Digestive

Access to the PDF text. Elle survient pendant le 2 e ou le 3 e trimestre de la grossesse.

Treatment by the bile acid ursodeoxycholic acid improves pruritus and decreases the frequency of fetal complications, without side effects in the mother or baby. Access to the text HTML. Access to the full text of this article requires a subscription. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.

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Bile acids, Ursodeoxycholic acid, Prematurity, Pruritus. Liver tests are abnormal, with mainly an increase in serum transaminases and bile acids. As per the Law relating to information storage and personal integrity, you have the right to oppose art 26 of that lawaccess art 34 of that law and rectify art 36 of travidique law your personal data.


Journal page Archives Contents list. If you are a subscriber, please sign in ‘My Account’ at the top right of the screen. It occurs during the second or third trimester. Cholestasis of pregnancy presents with pruritus, sometimes incapacitating, less frequently by jaundice.

Contact Help Who are we? In forms with severe choldstase, early delivery by induced labor between 37 and 38 weeks may be necessary. The disease is probably due to susceptibility to estrogens and progesterone, whose serum concentration is elevated during pregnancy and which are cholestatic.

Outline Masquer le plan. It is slightly more frequent during twin pregnancies.